Green tea compound Alzheimer hope

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Posted by Jane Lawman on January 02, 2008 at 02:16:41:

An ingredient of green tea may help to protect the brain
against the ravages of Alzheimer's disease, research in the US suggests.



Green tea contains many antioxidants, including those known as flavonoids,
that can protect against damage to the brain caused by charged particles called
free radicals.



Researchers report that a component of green tea prevented Alzheimer's-like
damage in the brains of mice genetically programmed to develop the
neurodegenerative disease process. The component, called epigallocatechin-3-gallate
(EGCG), is a major antioxidant in green tea and has been widely studied for its
reported protection against certain cancers.


Now the USF team provides the first evidence that EGCG
decreases production of the Alzheimer's-related protein, beta-amyloid,
which can accumulate abnormally in the brain and lead to nerve damage
and memory loss. This reduction in beta-amyloid was observed both in
cell cultures and a mouse model for Alzheimer's disease. EGCG appears
to block the initial process by which the Alzheimer's-related protein
is formed in brain cells.

Green tea contains many antioxidants, including those known as
flavonoids that can protect against free radical damage to the brain.




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